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Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.


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Charlie's the owner of The Electrocuted Gremlin, the world's dingiest pub. He's in love with his waitress, owes money to the mob, and has to deal with regulars like forgotten...


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Fascination with the scientific advances that were rapidly changing the world motivated Berenice Abbott to use photography as the friendly interpreter of science. Documenting...


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Simon Winchester, New York Times bestselling author of The Professor and the Madman, examines the legendary annihilation in 1883 of the volcano-island of Krakatoa, which was...


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A la tristesse du départ de l’être cher et la souffrance qui en découle, succède la difficile transformation à opérer. Au fil des textes, s’amorce un détachement lent et...


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